Non-Malaysian citizens are subject to 6% SST, to be verified and paid at the counter before screening.
Thyroglobulin Antibody (TGAb) Test
Introduction
Thyroglobulin Antibody (TGAb) is an autoantibody targeting thyroglobulin, a protein produced by the thyroid gland. A positive TGAb result suggests an autoimmune reaction against thyroid tissue, commonly associated with Hashimoto’s thyroiditis, hyperthyroidism, and hypothyroidism.
Why Take a TGAb Test?
- Autoimmune thyroid disease screening: Along with TPOAb, it is a key marker for Hashimoto’s thyroiditis.
- Thyroid disorder diagnosis: Helps determine the cause of hypothyroidism or hyperthyroidism.
- Disease risk prediction: A positive TGAb may indicate increased risk of future thyroid disease.
- Treatment monitoring: Useful for follow-up in thyroid disease management.
Method & Workflow
A venous blood sample is analyzed for TGAb levels. Results should be interpreted with TSH, FT3, FT4, and TPOAb.
Who Should Consider Testing?
- Patients with abnormal thyroid function (hyperthyroidism, hypothyroidism)
- Suspected cases of Hashimoto’s thyroiditis
- Individuals with family history of thyroid or autoimmune disorders
- Women planning pregnancy or during pregnancy
Frequently Asked Questions (FAQ)
Q1: What does a positive TGAb mean?
A: It indicates autoimmune thyroid activity, often linked to Hashimoto’s thyroiditis, hyperthyroidism, or hypothyroidism.
Q2: What is the difference between TGAb and TPOAb?
A: TGAb targets thyroglobulin, while TPOAb targets thyroid peroxidase. Both are usually tested together for accuracy.
Q3: Does a positive TGAb always require treatment?
A: Not necessarily. It depends on thyroid function and clinical symptoms. Regular monitoring may be recommended.
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Pre-Screening Preparation